The cGMP Advanced Cell and Biologic Products Manufacturing Facility occupies 11,000 square feet of space and is dedicated to processing various types of human tissue and cells. It is located on the fourth floor of the Diabetes Research Institute, University of Miami Miller School of Medicine Campus. Three clean room suites, certified to meet ISO-Class 7 standards, are utilized for cell and device manufacture. Three additional laboratories provide ample space for R&D activities. The Facility includes a Regulatory Unit, three additional laboratories dedicated to R&D and translational work, a dedicated cleaning and sterilization facility, and a raw material receipt, qualification, and storage space. The Facility’s leadership team possesses unique qualifications that have contributed to the development of this resource into an outstanding core asset for UM and extramural translational research, and clinical applications.